SHELF / USMLE Step 2 Practice Questions > Internal Medicine > Endocrinology

SHELF / USMLE Step 2 Practice Questions > Internal Medicine > Endocrinology

26 Case based vignette style practice questions from the American College of Physicians (ACP) with answers & thorough explanations - DOWNLOAD the .pdf

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Med-Spot on Med-Source: Diabetes & Stem Cells

Med-Spot - Diabetes & Stem Cells

Preliminary Study Results: 4.16. 07 Brazilian and US scientists have used autologous stem cell transfusions to allow type 1 diabetics to forgo insulin use.

Insulin producing beta cells in the pancreas. (UCHSC)

• The Pros
• 13 of 15 patients remain insulin free, and are off all diabetic medications.
• “It’s the first time in the history of type 1 diabetes where people have gone with no treatment whatsoever ... no medications at all, with normal blood sugars,” said study co-author Dr. Richard Burt of the Feinberg School of Medicine.
  
• The Cons
  
• Patients must undergo stem cell harvesting followed by high-does chemo and then stem cell transplant requiring a 3 week hospitalization.
• Patients face standard chemotherapy side effects and risk of lethal infection while immunocompromised.
  
• check out the article here - Voltarelli JC, et al. 2007. Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus. JAMA 297:1568-1576.

Algorithms: Endocrine

• Thyroid Nodule
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